Dapsone 5% gel: a new option in topical therapy for acne.

نویسنده

  • J Tan
چکیده

Dapsone 5% gel for the topical treatment for acne vulgaris was recently introduced in Canada. It represents the first new anti-acne agent to gain North American regulatory approval in the past decade. Dapsone's utility is attributable to its anti-inflammatory and antimicrobial properties that improve both inflammatory and non-inflammatory acne, with more prominent effects occurring in inflammatory lesions. Short- and long-term safety and efficacy have been demonstrated. Especially for patients exhibiting sensitivities or intolerance to conventional anti-acne agents, topical dapsone is a novel addition to the treatment armamentarium.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

A Study of the Efficacy of 5% Dapsone Gel as a Topical Therapy for Acne Vulgaris

Background: Effective treatment of Acne vulgaris (AV) is to reduce both severity and potential recurrence of the disease. Topical therapies remain the most common treatment option for mild-to-moderate AV. Objective: To evaluate the efficacy of dapsone gel 5% in the treatment of AV. Methods: This cohort study included 80 patients with AV , their ages range between 13-27 years, Acne severity was ...

متن کامل

Formulation and in vitro Evaluation of Dapsone Topical Gel 5%

Abstract Introduction: Dapsone gel (5%) is found to be effective in treating acne. The study was to develop a topical formulation of dapsone in Iran. Objective: Determination of appropriate formulation for generic form of this drug in the treatment of acne. Materials and Methods: Samples of the base of gel were made in the range of 0.3%-5% by dissolving Carbomer 934P in distilled water, and ...

متن کامل

Dapsone 7.5% Gel: A Review in Acne Vulgaris.

Dapsone 7.5% gel (Aczone®) is indicated for the once-daily topical treatment of acne vulgaris in patients aged ≥12 years. Dapsone is a sulfone antibacterial with anti-inflammatory actions, which are thought to be largely responsible for its efficacy in treating acne vulgaris. In two phase III trials of 12 weeks' duration in patients aged ≥12 years with moderate acne vulgaris, once-daily dapsone...

متن کامل

What's new in acne and rosacea?

Acne and rosacea are common conditions seen every day by dermatologists. This review will discuss the most recent therapeutic options for patients with these conditions. Specifically, for acne, there will be a discussion of the use of isotretinoin at higher cumulative doses as well as a new formulation of isotretinoin, isotretinoin-lidose. Adult women with acne represent a growing population of...

متن کامل

Adapalene in treatment of Acne Vulgaris: A review article

The inefficiency of current therapies of acne vulgaris, side effects and teratogenicity of topical and oral retinoids resulted in the need to find out new drugs. Adapalene 0.1% gel or solution with retinoid properties is effective in treatment of acne, and improves both inflammatory and non-inflammatory lesions. The anti-inflammatory properties of adapalene and its specific tendency to bi...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Skin therapy letter

دوره 17 8  شماره 

صفحات  -

تاریخ انتشار 2012